Table 4.
Model 1 1 | Model 2 2 | |||||
---|---|---|---|---|---|---|
β | 95% CI | p | β | 95% CI | p | |
CERAD Immediate Learning | 0.05 | 0.00–0.11 | 0.04 | 0.03 | −0.02–0.09 | 0.20 |
Digit Symbol Substitution Test | 0.06 | 0.01–0.11 | 0.02 | 0.06 | 0.01–0.10 | 0.02 |
Animal Fluency Test | 0.01 | −0.04–0.06 | 0.70 | 0.04 | −0.02–0.10 | 0.20 |
CERAD Delayed Recall | 0.05 | 0.01–0.09 | 0.01 | 0.04 | −0.01–0.08 | 0.08 |
Global Cognition | 0.06 | 0.02–0.08 | 0.004 | 0.06 | 0.01–0.08 | 0.02 |
1 Model 1 is unadjusted, accounting for MedD scores only. Sample sizes for each cognitive test were: Consortium to Establish a Registry for Alzheimer’s Disease–Immediate Learning (n = 2857); Digit Symbol Substitution Test (n = 2778); Animal Fluency Test (n = 2842); Consortium to Establish a Registry for Alzheimer’s Disease–Delayed Recall (n = 2855); Global Cognition (n = 2711). 2 Model 2 is adjusted for all covariates: age, sex, BMI, race/ethnicity, ratio of family income to poverty level, marital status, smoking status, diabetes status, history of cardiovascular disease, history of hypertension, and history of stroke. Sample sizes for cognitive test analyses were reduced from the original sample due to missing covariate data. Sample sizes for each cognitive test were: Consortium to Establish a Registry for Alzheimer’s Disease–Immediate Learning (n = 2596); Digit Symbol Substitution Test (n = 2533); Animal Fluency Test (n = 2583); Consortium to Establish a Registry for Alzheimer’s Disease–Delayed Recall (n = 2594); Global Cognition (n = 2471).