Table 3.
Odds ratios (OR) and 95% confidence intervals (CI) for the association between dietary pattern scores and prostate cancer risk, overall and by tumor grade, PROtEuS, Montreal, Canada, 2005–2012 1.
Quartiles of Dietary Pattern Score | 1991 Controls | All Prostate Cancers 1917 Cases | Low-Grade Prostate Cancers 2 1385 Cases | High-Grade Prostate Cancers 3 529 Cases |
---|---|---|---|---|
n | n Cases/OR (95% CI) | n Cases/OR (95% CI) | n Cases/OR (95% CI) | |
Healthy Eating | ||||
1 | 497 | 499/1.00 (reference) | 335/1.00 (reference) | 163/1.00 (reference) |
2 | 499 | 505/0.95 (0.78–1.15) | 378/1.07 (0.86–1.32) | 126/0.75 (0.57–0.99) |
3 | 497 | 477/0.84 (0.68–1.02) | 343/0.91 (0.73–1.14) | 133/0.77 (0.58–1.02) |
4 | 498 | 436/0.76 (0.61–0.93) | 329/0.90 (0.71–1.13) | 107/0.66 (0.48–0.89) |
ptrend = 0.004 | ptrend = 0.16 | ptrend = 0.008 | ||
Western Salty and Alcohol | ||||
1 | 498 | 457/1.00 (reference) | 325/1.00 (reference) | 132/1.00 (reference) |
2 | 498 | 482/0.92 (0.76–1.13) | 331/0.88 (0.70–1.10) | 149/0.99 (0.75–1.32) |
3 | 497 | 482/0.87 (0.71–1.06) | 355/0.88 (0.71–1.10) | 126/0.82 (0.61–1.10) |
4 | 498 | 496/0.89 (0.72–1.09) | 374/0.91 (0.73–1.14) | 122/0.78 (0.58–1.06) |
ptrend = 0.21 | ptrend = 0.59 | ptrend = 0.05 | ||
Western Sweet and Beverages | ||||
1 | 498 | 388/1.00 (reference) | 285/1.00 (reference) | 103/1.00 (reference) |
2 | 498 | 442/1.01 (0.82–1.24) | 325/0.96 (0.76–1.20) | 117/0.96 (0.70–1.30) |
3 | 498 | 494/1.12 (0.91–1.38) | 360/1.01 (0.80–1.27) | 134/1.06 (0.78–1.45) |
4 | 497 | 593/1.35 (1.10–1.66) | 415/1.14 (0.91–1.44) | 175/1.32 (0.98–1.80) |
ptrend = 0.002 | ptrend = 0.23 | ptrend = 0.02 |
1 Adjusted for age, ancestry, education, first-degree family history of prostate cancer, and timing of last prostate cancer screening. 2 Prostate cancer cases with a Gleason score ≤ 6, or of 7 with a primary score of 3. 3 Prostate cancer cases with a Gleason score of 7 with a primary score of 4, or ≥ 8. Information on the primary or secondary score was missing for 3 cases.