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. 2020 Jul 19;9(7):423. doi: 10.3390/antibiotics9070423

Table A3.

Saving of the RDL no. 16/2012 introduction by active substance (predictions with the ARIMA models in Table A2).

Series
Active Substance
Packages
Doxycycline
Packages
Cloxacillin
Date Real Value Prediction Confidence Interval (80%) Real Value Prediction Confidence Interval (80%)
Jun. 2013 1410 1310 1217–1403 2475 2308 2160–2456
Jul. 2013 1009 1302 1210–1,395 2371 2437 2398–2476
Aug. 2013 802 1053 954–1151 2168 2441 2376–2506
Sep. 2013 1211 1319 1215–1423 1985 2469 2383–2555
Oct. 2013 1308 1628 1518–1737 1790 2431 2329–2533
Nov. 2013 1342 1659 1545–1774 1641 2349 2233–2464
Dec. 2013 1234 1543 1424–1662 1536 2281 2154–2407
Jan. 2014 1425 1745 1621–1869 1544 2218 2081–2354
Feb. 2014 1458 1794 1666–1923 1567 2230 2085–2375
Mar. 2014 1490 1902 1769–2035 1565 2242 2089–2395
Apr. 2014 1347 1792 1655–1930 1557 2317 2157–2477
May 2014 1271 1694 1553–1835 1545 2356 2189–2522
Jun. 2014 965 1517 1372–1662 1521 2379 2207–2551
Total 16,272 20,258 23,265 30,458
Difference −3986 −7193
Variation −19.68% −23.62%
Stockpiling effect
(var. Jun. 2013)
7.63% 7.23%
Series
Active Substance
Packages
Amoxicillin
Packages
Amoxicillin and Beta-Lactamase Inhibitors
Date Real Value Prediction Confidence Interval (80%) Real Value Prediction Confidence Interval (80%)
Jun. 2013 34,671 31,763 28,860–34,662 25,897 23,889 22,018–25,760
Jul. 2013 22,177 25,553 22,672–28,433 21,009 24,240 22,400–26,079
Aug. 2013 17,158 21,420 17,719–25,122 19,012 23,343 21,266–25,421
Sep. 2013 24,811 30,277 26,127–34,427 21,377 25,021 22,944–27,098
Oct. 2013 31,244 35,922 31,504–40,340 21,151 28,156 26,079–30,233
Nov. 2013 36,462 41,326 36,742–45,910 18,909 27,648 25,571–29,725
Dec. 2013 31,615 43,703 39,014–48,393 23,170 29,024 26,947–31,101
Jan. 2014 29,702 42,492 37,735–47,248 23,802 32,634 30,557–34,711
Feb. 2014 24,601 43,483 38,684–48,283 18,246 31,123 29,046–33,200
Mar. 2014 25,047 43,360 38,532–48,188 18,852 31,016 28,939–33,093
Apr. 2014 21,518 33,168 28,322–38,014 17,605 26,614 24,536–28,691
May 2014 20,855 37,643 32,785–42,501 17,288 27,619 25,541–29,696
Jun. 2014 20,149 34,337 29,471–39,202 16,864 25,570 23,493–27,647
Total 340,010 464,447 263,182 355,897
Difference −124,437 −92,715
Variation −26.79% −26.05%
Stockpiling effect
(var. Jun. 2013)
9.16% 8.40%

Legend: RDL (Royal Decree-Law). Source: Own elaboration based on data provided by the Basque Government Pharmacy Department.