Table 2.
Gene ontology enrichment analyses of the genes associated with the top 100 CpG sites.
| Category 1 | Term | p-Value 2 | Genes |
|---|---|---|---|
| MF | GO:0042169~SH2 domain binding | 0.002 | SYP, NLK, DAG1 |
| BP | GO:0006355~regulation of transcription, DNA-templated | 0.005 | ASXL2, PKNOX2, ZNF718, BPTF, TFEC, NLK, SCML1, GAS7, BRD8, KLF3 |
| CC | GO:0005634~nucleus | 0.011 | ANP32C, NLK, ANP32E, SCML1, TKT, CAMKK1, TNKS2, PKNOX2, PSMA1, SERPINB9, ZNF718, FAM64A, SENP1, TAF15, BPTF, C19ORF66, USP36, FANCC, BRD8, MYH10, KLF3 |
| BP | GO:1903955~positive regulation of protein targeting to mitochondrion | 0.016 | HSPA1L, NBPF3, USP36 |
| CC | GO:0005654~nucleoplasm | 0.020 | ASXL2, NLK, FANK1, DAG1, TKT, HSPA1L, PSMA1, SENP1, BPTF, TAF15, TFEC, BRD8, FANCC |
| CC | GO:0000812~Swr1 complex | 0.021 | ANP32E, BRD8 |
| BP | GO:0043486~histone exchange | 0.025 | ANP32C, ANP32E |
| BP | GO:0071310~cellular response to organic substance | 0.038 | SYP, CASP1 |
1 BP: biological process; CC: cellular component; MF: molecular function; 2 Terms with a p-value ≤ 0.05 are shown.