Table 2. Seizure Frequency.
| Variable | No. (%) | ||
|---|---|---|---|
| KD (n = 52) | MAD (n = 52) | LGIT diet (n = 54) | |
| Seizure frequency at 24 wk | |||
| Median (IQR) | 3.3 (1.2 to 14) | 4 (0.5-10) | 4 (0.4-11) |
| Mean (SD) | 9.4 (14) | 11 (19) | 8.7 (12) |
| Achieved specific cutoff points after 24 wk of intervention | |||
| Complete resolution | 6 (11.5) | 8 (15.4) | 9 (16.7) |
| >90% Reduction | 6 (11.5) | 6 (11.5) | 8 (14.8) |
| >50% Reduction | 23 (44.2) | 13 (25.0) | 15 (27.8) |
| ≤50% Reduction | 13 (25.0) | 14 (26.9) | 15 (27.8) |
| Increase in seizure frequency at 24 wk | 4 (7.7) | 11 (21.2) | 7 (12.9) |
| % Change in seizure frequency | |||
| Per-protocol analysis | |||
| Median (IQR) | −67 (−87 to −37) | −57 (−92 to −5.5) | −60 (−92 to −24) |
| Mean (SD) | −60 (33) | −48 (46) | −55 (40) |
| Intention-to-treat analysis | |||
| Median (IQR) | −66 (−85 to −38) | −45 (−91 to −7) | −54 (−92 to −19) |
| Mean (SD) | −60 (32) | −46 (45) | −52 (41) |
Abbreviations: IQR, interquartile range; KD, ketogenic diet; LGIT, low glycemic index therapy; MAD, modified Atkins diet.