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. 2020 Jul 9;8(7):203. doi: 10.3390/biomedicines8070203

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Prophylaxis with MV130 modulates serum cytokine, chemokine and growth factor secretion pattern. Cytokines (upper panels), chemokines (left bottom panel) and growth factors (right bottom panel) secreted in serum one year following MV130 administration determined by Luminex technique. Fold induction relative to basal level (before MV130 treatment) is shown. Undetectable values were found for IL-2, IL-5, IL-10, IL-12(p70), IL-15, GM-CSF, RANTES and VEGF. Data from 9–10 subjects are shown as mean ± SEM of fold increase. Outliers were identified by means of Tukey’s range test on represented values. Normal distribution was evaluated using the Shapiro–Wilk test. p values were calculated using one-sample t-test with a theoretical value of 1 (no fold induction). * p < 0.05.