Table 1.

Neurocognitive functions’ alterations and psychological diseases in CF subjects.

Neurocognitive Alteration/Psychological Symptoms	Authors
Depression and anxiety symptoms	Cronly J et al., 2018 [22]
Executive functions, memory and attention alterations	Piasecki B et al., 2016 [11]
Logical, conceptual and abstract thinking deficits Lower cognitive flexibility Reduced ability to change the course of reasoning in response to changing circumstances	Maddrey MA et al., 1998 [39] Crews WDJR et al., 2000 [40] Crews WDJR et al., 2003 [41] Hoffman BM et al., 2012 [12]
Sleep disturbances	Bradley S et al., 1999 [80] De Castro-Silva C et al., 2010 [43] Spicuzza L et al., 2012 [44] Button BM et al., 2016 [84] Vandeleur M et al., 2017 [45]
Worsening of anxiety and depression in female adolescent patients on modulators therapy	McKinzie et al., 2017 [85]