Figure 5.

Hepatic concentration of low molecular weight thiols and cytokine profile in C57BL/6 wild-type mouse livers at 8 weeks from the initial concurrent diethylnitrosamine (DEN) injection and thioacetamide (TAA) administration. Tissue thiol concentration: homocysteine (A), N-acetyl cysteine (B), Cysteinyl-glycine (C) and Cysteine (D). Cytokine concentration: (E) Tumor necrosis factor (TNF)-α, (F) interleukine (IL)-6, (G) IL-17 and (H) granulocyte-monocyte colony stimulating factor (GM-CSF). Results are expressed as mean ± SEM (n = 4−6). * Indicates statistical differences (Tukey–Kramer’s test, p < 0.05) to DEN/TAA-treated animals not receiving PIs.