Table 2.
Alignment of PorA SA Determinant Region between Sequence Types.
| Sequence a,b,c | cgMLST200-12 vs. MLST-8 d |
Description | |
|---|---|---|---|
| 170- | * * * * * * * * * * * | −209 | Conserved residues |
| NCTC11168 | FMAAEQGADLLEHSNISTTS NQAPFKVDSVGNLY | Reference sequence | |
| N48272F | FMAEEQGADLLGKST ISTTQKAAPFQADSLGNLY | 55:53 | SA clonal sequence |
| N43804F | FMAEEQGADLLGKST ISIT QKAAPFQADSLGNLY | 1:1 | Substitution not in SA loci |
| N45191FR | FMAEEQGT DLLGKST ISTTQKAAPFQADSLGNLY | 1:1 | Substitution not in SA loci |
| N46355F | FMAEEQGADLLGKSTISTT QKAAPFQTNSLGNLY | 1:1 | Substitution in SA loci |
| N49694F | FMEKEQ I S DLVG SNSSTFNVDSI GNLY | 16:16 | Deletion and substitutions in SA loci |
| N44409F | FMAAEQSS DLVG ANGSAFKVDSI ENLY | 1:1 | Deletion and substitutions in SA loci |
| N45200F | FMAKEQGSDLVG ANGSAFNVDSIGNLY | 1:1 | Deletion and substitutions in SA loci |
a * indicates conserved residue at sequence position, b Bold formatting indicates amino acid substitution associated with the SA phenotype, c Underline formatting indicates amino acid substitution not associated with the SA phenotype, d cgMLST200-12 (left) and MLST-8 (right) isolates identified with the corresponding PorA aa sequence.