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Reproduction of the open gingival embrasure (OGE) model and experimental design. Activated wire (a), spring-papilla distance (SPD, arrow) (b), attached wire frontal (c), lateral (d), and lingual (e) views. (f) Experimental design, showing wire attachment for IDP loss, injection of phosphate-buffered saline (PBS) or hyaluronic acid (HA) filler, and sacrifice schedule.
