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(A) Binding mode of compound 25 depicted as a 2D diagram. The figure was produced using the “Ligand interaction” feature of MOE. (B) The proposed binding mode of compound 25 in the S. aureus FtsZ protein. Compound 25 and surrounding protein sidechains are displayed in stick representation. The backbone from the protein is shown as cartoon. The picture was generated using Pymol (http://pymol.org) software.
