Table 1.
Antimicrobial resistance, virulence factors, and molecular characteristics of methicillin-resistant Staphylococcus aureus (MRSA) strains isolated from blood cultures.
| Isolate | Antimicrobial Resistance | Virulence | Molecular Typing | ||||
|---|---|---|---|---|---|---|---|
| Phenotype | Genotype a | MLST (CC) | spa | SCCmec | agr | ||
| VS2761 | FOX, PEN, ERY, DA 1, CIP | mecA, ermC, msr(A/B) | hlA | 22 (22) | t747 | IV | I |
| VS2762 | FOX, PEN, ERY, DA 2, CN, CIP | mecA, blaZ, ermA, msr(A/B), aac(6’)-Ie-aph(2’’)-Ia | hlA | 105 (5) | t002 | II | II |
| VS2763 | FOX, PEN, CIP | mecA, blaZ | hlA, hlB, etA | 22 (22) | t747 | IV | I |
| VS2764 | FOX, PEN, ERY, DA 2, CIP | mecA, blaZ, ermC, msr(A/B), mphC | hlA, etA | 22 (22) | t747 | IV | I |
| VS2765 | FOX, PEN, ERY, DA 2, CIP | mecA, blaZ, ermC, msr(A/B), mphC | lukF/lukS-PV, hlA, hlB, etA | 22 (22) | t747 | IV | I |
| VS2766 | FOX, PEN, ERY, DA 1, CN, TOB, CIP | mecA, blaZ, ermC, msr(A/B), mphC, aac(6’)-Ie-aph(2’’)-Ia, ant(4’)-Ia | lukF/lukS-PV, hlA, hlB, etA | 22 (22) | t020 | IV | I |
| VS2767 | FOX, PEN, CIP | mecA, blaZ | hlA, hlB, etA | 22 (22) | t747 | IV | I |
| VS2768 | FOX, PEN, ERY, DA 2, CIP | mecA, blaZ, ermC, msr(A/B), mphC | lukF/lukS-PV, hlA, etA | 22 (22) | t747 | IV | I |
| VS2769 | FOX, PEN, ERY, DA 2, CIP | mecA, blaZ, msr(A/B), mphC | hlA, hlB | 5 (5) | t002 | II | II |
| VS2770 | FOX, PEN, ERY, DA 2, CIP, FD | mecA, blaZ, ermA, ermC, msr(A/B), mphC | hlA, hlB | 5984 | t1084 | II | II |
| VS2771 | FOX, PEN, ERY, DA 2, CIP | mecA, blaZ, ermC, msr(A/B), mphC | hlA | 8 (8) | t008 | IV | I |
| VS2772 | FOX, PEN, CIP | mecA, blaZ | hlB | 5 (5) | t002 | II | II |
| VS2773 | FOX, PEN, ERY, DA 2, CIP | mecA, blaZ, ermA, ermC, msr(A/B), mphC | hlB | 105 (5) | t10682 | II | II |
| VS2774 | FOX, PEN, ERY, DA 1, CIP | mecA, blaZ, ermA, mphC | hlB, etA | 22 (22) | t18526 | IV | I |
| VS2775 | FOX, PEN, ERY, DA 2, CIP | mecA, blaZ, ermA, ermC, msr(A/B) | hlB, etA | 22 (22) | t1370 | IV | I |
| VS2776 | FOX, PEN, FD | mecA, blaZ | hlB | 8 (8) | t008 | IV | I |
1 Constitutive MLSB (cMLSB) phenotype; 2 Inducible MLSB (iMLSB) phenotype; FOX: cefoxitin; PEN: penicillin; ERY: erythromycin; DA: clindamycin; CN: gentamicin; TOB: tobramycin; CIP: ciprofloxacin; FD: fusidic acid; MLST: multilocus sequence typing; ST: sequence type; CC: clonal complex; SCCmec: staphylococcal cassette chromosome mec; a mecA gene encodes the protein PBP2A; blaZ encodes the protein BlaZ; erm genes encode the rRNA adenine N-6-methyltransferase, msr(A/B) encodes the peptide methionine sulfoxide reductase; mphC encodes the macrolide 2’-phosphotransferase; aac(6’)-Ie-aph(2’’)-Ia encodes the bifunctional enzyme AAC/APH; and ant(4’)-Ia encodes the aminoglycoside O-nucleotidyltransferase ANT(4’)-Ia