Figure 9.

Representation of the structural changes in TSWV segment S hairpin caused by the U165A mutation. Using RNAmute, the model was generated for accession AY744468 and naturally occurring mutation (U165A). (A) Representation of the hairpin, the mutation, and the predicted effect on the secondary structure. The red horizontal line represents predicted structural change. The probability of the structure is color coded. (B) Hairpin structure in wild type and mutant sequence. The U165A mutation is indicated in yellow. Orange boxes indicate covariant sites predicted to emerged after the initial mutation.