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. 2020 Jul 9;20(3):2721–2728. doi: 10.3892/ol.2020.11837

Figure 1.

Figure 1.

Exosomal miR-34b is downregulated in ovarian cancer. (A) Electron microscopy analysis of exosomes isolated from the SKOV3 conditioned medium. Arrows indicate the exosomes. Scale bar, 100 nm. (B) Size distribution graph of exosomes isolated from the SKOV3 conditioned medium and quantified using nanoparticle tracking analysis. (C) Western blotting of the exosomal markers, CD63 and TSG101, in exosomes isolated from IOSE-80 and SKOV3 conditional medium. (D) Relative expression levels of miR-34b in IOSE-80 and SKOV3 cells and exosomes. **P<0.01 vs. IOSE-80. miR, microRNA.