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. 2020 Jun 19;20(3):2369–2377. doi: 10.3892/ol.2020.11762

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Copyright: © Liu et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 3. — T7-MUC1 conjugate induces a cytolytic response in cells expressing high levels of MUC1 protein. (A) MUC1 expression in MCF-7, MB231 and K562 cells. (B-D) Induction of the CTL effect on (B) MCF-7, (C) K562 and (D) MB231 cells. The groups are as follows: A, T7-MUC1 conjugate added on day 3; B, MUC1 added on day 3; C, T7-MUC1-conjugate added on day 5; D, MUC1 added on day 5; and E, control with no added antigen. Data are presented as the mean ± SD; n=5. *P<0.05 vs. E. MUC1, mucin 1; T7, Toll-like receptor 7 agonist; PBMCs, peripheral blood mononuclear cells; CTL, cytotoxic T lymphocytes.