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. 2020 Jun 29;12(7):1932. doi: 10.3390/nu12071932

Figure 2.

Figure 2

Effects of the high-fat and high-cholesterol diet and metformin supplementation on (a) hepatic histology, (b) liver weight, (c) liver to body weight ratio, (d) serum alanine aminotransferase (ALT) and (e) serum aspartate aminotransferase (AST) in the male mice: Hepatic sections were stained with hematoxylin and eosin. Data are expressed as means ± SD ((a): n = 6; (b–e): n = 9–15 per group). * p < 0.05 as determined by one-way ANOVA followed by LSD post hoc test. NC, normal diet; HFC, high-fat and high-cholesterol diet; HFC + Met, HFC with metformin supplementation. Scale bar: 200 μm.