Table 2.
Associations of the 4-SNP GRS on obesity-related traits.
| GRS < 3 Risk Alleles (N = 123) |
GRS ≥ 3 Risk Allele (N = 172) |
* p Value | |
|---|---|---|---|
| BMI (kg/m2) | 26.13 ± 0.45 | 26.85 ± 0.37 | 0.24 |
| WC (cm) | 87.13 ± 1.15 | 89.14 ± 0.92 | 0.19 |
| WHR | 2.27 ± 0.98 | 0.88 ± 0.01 | 0.18 |
| Visceral fat (%) | 7.89 ± 0.71 | 8.08 ± 0.55 | 0.43 |
| Body fat (%) | 31.75 ± 1.32 | 33.87 ± 1.02 | 0.15 |
* p Values obtained from the linear regression analysis adjusted for age, sex and additionally for BMI when BMI is not an outcome. The analysis was performed on log-transformed variables. Abbreviations: SNP: single nucleotide polymorphism; GRS: genetic risk score; BMI: body mass index; WC: waist circumference; WHR: waist–hip ratio.