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. 2020 Aug 3;11:3872. doi: 10.1038/s41467-020-17672-w

Table 2.

Baseline cost-effectiveness analysis in Markov models.

Cost ($) Incremental cost ($) Effectiveness(QALYs) Incremental effectiveness ICER ($/QALY)
Patients in group Ia
  The least intensive NCCN strategy 9187 0 36.049 0 0
  The moderately intensive NCCN strategy 11,138 1951 36.734 0.685 2848
  The most intensive NCCN strategy 15,699 6512 37.333 1.284 5072
  The RTOG strategy 11,273 2050 36.780 0.732 2800
  The risk-based strategyb 9372 185 36.142 0.093 1957
Patients in group IIa
  The least intensive NCCN strategy 12,479 0 26.627 0 0
  The moderately intensive NCCN strategy 15,298 2819 27.596 0.969 2909
  The most intensive NCCN strategy 19,911 7432 28.288 1.661 4474
  The RTOG strategy 15,732 3253 27.734 1.107 2939
 The risk-based strategyb 14,869 2390 27.620 0.993 2407
Patients in group IIIa
  The least intensive NCCN strategy 14,815 0 21.626 0 0
  The moderately intensive NCCN strategy 17,821 3006 22.514 0.888 3385
  The most intensive NCCN strategy 22,135 7320 23.040 1.414 5177
  The RTOG strategy 18,333 3518 22.690 1.064 3306
  The risk-based strategyb 17,864 3049 22.619 0.993 3070
Patients in group IVa
  The least intensive NCCN strategy 15,970 0 20.264 0 0
  The moderately intensive NCCN strategy 19,111 3141 21.146 0.882 3561
  The most intensive NCCN strategy 23,367 7397 21.645 1.381 5356
  The RTOG strategy 19,546 3576 21.317 1.053 3396
  The risk-based strategyb 19,564 3594 21.377 1.113 3229

QALY, quality-adjusted life years; ICER, incremental cost-effectiveness ratio; NCCN, National Comprehensive Cancer Network; RTOG, Radiation Therapy Oncology Group.

aPatients were grouped according to TNM stages and EBV DNA.

bThe dominant strategy.