Table 2.
Comparison of per-tile predictions of the T- and B-cell model to the real number of T and B cells.
T-cell model | B-cell model | |
---|---|---|
Correlation coefficient with # T cells on the H&E/CD3-stained slide | 0.51 | 0.39 |
AUC threshold 10 T cells | 0.79 | 0.73 |
AUC threshold 20 T cells | 0.86 | 0.79 |
AUC threshold 25 T cells | 0.89 | 0.83 |
AUC threshold 51 T cells | 0.93 | 0.90 |
Correlation coefficient with # B cells on the H&E/CD20-stained slide | 0.19 | 0.23 |
AUC threshold 0 B cells | 0.68 | 0.66 |
AUC threshold 3 B cells | 0.74 | 0.76 |
AUC threshold 5 B cells | 0.78 | 0.82 |
AUC threshold 11 B cells | 0.81 | 0.89 |
Comparaison was calculated respectively from the HE/CD3 and HE/CD20 double-stained slides. For the HE/CD3 slide (respectively HE/CD20), we display the correlation between the tile-level predictions of each model and the number of T cells (respectively B cells) per tile, as well as the AUC for distinguishing tiles that contain more T cells (respectively B cells) than a given threshold (respectively 75th, 90th, 95th, and 99th percentiles).