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. 2020 Aug 3;11:3877. doi: 10.1038/s41467-020-17678-4

Table 2.

Comparison of per-tile predictions of the T- and B-cell model to the real number of T and B cells.

T-cell model B-cell model
Correlation coefficient with # T cells on the H&E/CD3-stained slide 0.51 0.39
AUC threshold 10 T cells 0.79 0.73
AUC threshold 20 T cells 0.86 0.79
AUC threshold 25 T cells 0.89 0.83
AUC threshold 51 T cells 0.93 0.90
Correlation coefficient with # B cells on the H&E/CD20-stained slide 0.19 0.23
AUC threshold 0 B cells 0.68 0.66
AUC threshold 3 B cells 0.74 0.76
AUC threshold 5 B cells 0.78 0.82
AUC threshold 11 B cells 0.81 0.89

Comparaison was calculated respectively from the HE/CD3 and HE/CD20 double-stained slides. For the HE/CD3 slide (respectively HE/CD20), we display the correlation between the tile-level predictions of each model and the number of T cells (respectively B cells) per tile, as well as the AUC for distinguishing tiles that contain more T cells (respectively B cells) than a given threshold (respectively 75th, 90th, 95th, and 99th percentiles).