Table 4.
ROC-AUCs for the prediction of MSI status in two extreme regimes.
| Regime | Dataset | Transcriptomic (this paper) | WSIs (this paper) | WSIs. (ref. 56) |
|---|---|---|---|---|
| 1 (100% of data in hospital B) | TCGA-CRC-DX | — | 0.82 | 0.77 |
| 1 | TCGA-CRC-KR | — | 0.83 | 0.84 |
| 1 | TCGA-STAD | — | 0.76 | 0.81 |
| 2 (25% of data in hospital B) | TCGA-CRC-DX | 0.81 | 0.71 | 0.68 |
| 2 | TCGA-CRC-KR | 0.79 | 0.72 | 0.63 |
| 2 | TCGA-STAD | 0.66 | 0.63 | 0.65 |
In regime 1, 100% of the data in hospital B. In regime 2, 75% of the data in hospital A and 25% in hospital B. TCGA-CRC-DX: TCGA colorectal cancer dataset (FFPE slides), TCGA-CRC-KR: TCGA colorectal cancer dataset (frozen slides) and TCGA-STAD: Stomach adenocarcinoma.