Table 3.
Correlation between gene expression of the receptors for VIP and for thyroid hormone in PBMC. Spearman’s correlation test performed with the relative mRNA expression levels of VPAC1 or VPAC2 and Thyroid hormone receptors.
| Healthy donors (n = 18) |
Hyperthyroid GD (n = 9) |
Euthyroid GD (n = 5) |
||||
|---|---|---|---|---|---|---|
| VPAC1 | VPAC2 | VPAC1 | VPAC2 | VPAC1 | VPAC2 | |
| THRA | 0.3609** | − 0.0329 | 0.3059 | 0.4011* | 0.8464*** | 0.2714 |
| THRB | 0.4597*** | 0.4152 | 0.1068 | 0.232 | − 0.3107 | − 0.0964 |
| ITGAV | 0.4911*** | 0.6923*** | 0.1148 | 0.3553 | 0.6321* | 0.0678 |
| ITGB3 | − 0.4638*** | − 0.2129 | 0.2637 | 0.243 | − 0.0514 | − 0.1429 |
Spearman’s correlation coefficients (rho) are shown, and statistical signification is marked as *P < 0.05; **P < 0.001; ***P < 0.001. For more details, see “Methods” section.