C. nutans extract rescuing effect on LPS-induced ECs. In total, seven of the herb extracts including T. bellirica (extract 1), C. sappan (extract 2), G. lingzhi (extract 3), P. emblica (extract 4), K. parviflora (extract 5), T. chebula (extract 6), and C. nutans (extract 7) were screened for their activity to protect LPS-induced cell death in ECs. (A) Cells were treated with LPS in the presence of herb extracts at the sub-lethal dose for 24 h and the cell viability was measured using Prestoblue™ reagent (* indicates p < 0.05, ** indicates p < 0.01, and *** indicates p < 0.001). (B) The changes of cell morphology (upper) and nucleus staining (lower) upon LPS treatment were observed under the microscope. The red arrows indicated the fragments of nucleus. The scaled bar (20 micrometers) was indicated in red.