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. 2020 Jul 16;9(7):579. doi: 10.3390/pathogens9070579

Figure 1.

Figure 1

Body weight losses and increased rectal temperatures of outbred Hartley guinea pigs infected with the virulent P18 or rP18 strain of PICV as compared to those of animals infected with the avirulent P2 or rP2 strain. Outbred Hartley guinea pigs were either mock infected (with PBS) or infected with various PICV strains (P2, rP2, P18, or rP18). Each animal was monitored daily for body weight loss (normalized to day 0) (A) and rectal temperature change (B). Fever is defined as rectal temperature of >39.5 °C.