Table 1.

Guinea pigs infected with different virulent (P18 or rP18) and avirulent (P2 or rP2) PICV strains or PBS control and their disease phenotypes.

Guinea Pig ID	Viruses	Fever, BW Loss 1	DoE 2	Health, BW at DoE 3
867508	PBS	No fever, no BW loss	18 dpi	Healthy, BW 139%
867474	P2	Fever d6 to d9, BW loss d9 to d10	18 dpi	Healthy, BW 132%
867480	P18	Fever d5 to d13, BW loss since d8	14 dpi	Moribund, BW 74%
867488	rP18	Fever d5 to d17 BW loss since d9	18 dpi	Moribund BW 80%
867494	rS2L18	Fever d6 to d10 BW loss d9 to d10	18 dpi	Healthy, BW 116%
867500	rS18L2	Fever d6 to d13 BW loss d9 to d16	18 dpi	Healthy, BW 102%

¹ daily observation of rectal temperature and body weight (BW). ² DoE, date of euthanization, either on 18 dpi or when reaching terminal points. ³ BW at the date of euthanization was normalized to its BW at day 0 (set as 100%). TP, terminal points.