Table 1.
Action of estrogens on several immune parameters depending on their concentrations.
| ESTROGENS | |
|---|---|
| HIGH | LOW |
| Increased Treg | Decreased Treg |
| Th2 differentiation | Th1 differentiation |
| Reduced monocytes secretion of IL-1β, IL-6 and TNF | Increased monocytes secretion of IL-1β, IL-6 and TNF |
| Increased chemotactic capacity of neutrophils | Reduced chemotactic capacity of neutrophils |
| Mitigated cytotoxicity of natural killer (NK) cells | Stimulated cytotoxicity of natural killer (NK) cells |
| Increased differentiation and activation of dendritic cells | Reduced action on dendritic cells |