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. 2020 Jul 21;8(7):232. doi: 10.3390/biomedicines8070232

Table 1.

Action of estrogens on several immune parameters depending on their concentrations.

ESTROGENS
HIGH LOW
Increased Treg Decreased Treg
Th2 differentiation Th1 differentiation
Reduced monocytes secretion of IL-1β, IL-6 and TNF Increased monocytes secretion of IL-1β, IL-6 and TNF
Increased chemotactic capacity of neutrophils Reduced chemotactic capacity of neutrophils
Mitigated cytotoxicity of natural killer (NK) cells Stimulated cytotoxicity of natural killer (NK) cells
Increased differentiation and activation of dendritic cells Reduced action on dendritic cells