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. Author manuscript; available in PMC: 2020 Aug 4.
Published in final edited form as: Metabolism. 2018 Apr 15;85:286–297. doi: 10.1016/j.metabol.2018.04.006

Fig. 3. Chrebp deletion resulted in impaired fructose transport into the liver and impaired conversion to lactate in the intestine.

Fig. 3.

WT (n=8) and Chrebp KO (n=8) mice were fed either the control diet (CD) or high-fructose diet (HFrD) for 3 days starting at 8 weeks of age; they were then fasted for 2 h to achieve synchronization. Plasma levels of (A) ALT, (B) AST, (C) LDH, (D) triglyceride, and (E) total cholesterol, (F) liver triglyceride, and (G) liver cholesterol were measured from portal samples. Lactate levels in (H) the intestine and (I) liver were measured. Results are expressed as mean ± SEM. * p<0.05 vs. genotype-matched, CD-fed group; # p<0.05 vs. diet-matched, genotype control.