Table IV.
Diagnostic value of serum CEA, OPN and DKK1 in NSCLC.
| Diadynamic criteria | AUC | 95% CI | Standard error | Cut-off value | Sensitivity (%) | Specificity (%) |
|---|---|---|---|---|---|---|
| CEA | 0.818 | 0.745–0.891 | 0.037 | 21.34 (ng/ml) | 86.25 | 70.00 |
| OPN | 0.847 | 0.777–0.917 | 0.036 | 23.31 (ng/ml) | 71.61 | 91.25 |
| DKK1 | 0.838 | 0.772–0.904 | 0.033 | 43.39 (ng/ml) | 92.50 | 65.00 |
| CEA+OPN | 0.920 | 0.875–0.964 | 0.023 | 0.477 | 87.50 | 86.67 |
| CEA+DKK1 | 0.912 | 0.866–0.958 | 0.023 | 0.332 | 92.50 | 76.67 |
AUC, area under curve; 95% CI, 95% confidence interval; CEA, carcinoma embryonic antigen; OPN, osteopontin; DKK1, Dickkopf-1; NSCLC, non-small cell lung cancer.