Fig. 3.

RRM2 levels are highly correlated with PCS1 gene expression. Correlation of RRM2 level with PCS gene expression in TCGA (left), Taylor (middle), and SU2C/PCF (right) cohorts. Each individual patient sample is indicated by a single column (top plot) and a single dot (bottom plot). PCS scores were calculated with GSVA using the ssGSEA method, and the values were compared to RRM2 mRNA expression levels divided by quantiles. The differences between pairs are statistically significant except for those labeled as N.S. (not significant). Significance was determined using Wilcoxon's rank‐sum test.