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. 2020 Jul 16;12(7):2106. doi: 10.3390/nu12072106

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Results obtained from gastrocnemius muscle samples from all experimental groups: (a) gastrocnemius muscle polar extract PLS–DA plot score; gastrocnemius muscle polar extract identified metabolites, as normalized concentrations (µM); (b) 2-deoxyuridine; (c) nicotinurate; (d) NAD⁺ and NADP⁺; (e) muscle non-polar extract PLS–DA plot score. Legend: C, Control group (n = 7–8); W, Tumor-bearing group (n = 7); L, Group without tumors and with a maternal leucine-rich diet (n = 7–8); WL, Tumor-bearing group with a maternal leucine-rich diet (n = 8). For more details, see Material and Method section. ^a, p < 0.05 for statistical difference compared to C group; ^b, p < 0.05 for statistical difference compared to L group.

Results obtained from gastrocnemius muscle samples from all experimental groups: (a) gastrocnemius muscle polar extract PLS–DA plot score; gastrocnemius muscle polar extract identified metabolites, as normalized concentrations (µM); (b) 2-deoxyuridine; (c) nicotinurate; (d) NAD⁺ and NADP⁺; (e) muscle non-polar extract PLS–DA plot score. Legend: C, Control group (n = 7–8); W, Tumor-bearing group (n = 7); L, Group without tumors and with a maternal leucine-rich diet (n = 7–8); WL, Tumor-bearing group with a maternal leucine-rich diet (n = 8). For more details, see Material and Method section. ^a, p < 0.05 for statistical difference compared to C group; ^b, p < 0.05 for statistical difference compared to L group.