Figure 6.
Effect of TEMPOL on restoring FID in Hcy preconditioned arterioles. Isolated arterioles from obese subjects (n = 10) and non-obese controls (n = 10) were incubated in100 µM of Hcy and the superoxide dismutase mimetic, TEMPOL (10−5 M) for 180 min followed by measuring the FID. Charts (A) and (B) present the absolute increase in FID in response to combined incubation with Hcy and TEMPOL relative to Hcy alone in SAT and VAT arterioles, respectively. All measurements are presented as means ± standard error (SE). * (p < 0.05) for comparing obese subjects with controls.