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. 2020 Jul 15;12(7):2097. doi: 10.3390/nu12072097

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Biochemical measurements of a 32-year-old multiple sclerosis male who received 54,000 international units per day of vitamin D₃ for 4 months. Abbreviation: 1,25(OH)₂D: 1,25-dihydroxyvitamin D; 25(OH)D: 25-hydroxyvitamin D; PTH: parathyroid hormone. Note: Red solid line represents serum 25-hydroxyvitamin D levels. Blue solid line represents serum total calcium levels. Red highlight represents normal range for serum 25-hydroxytamin D (30–100 ng/mL/75–250 nmol/L). Blue dashed line represents normal range for serum total calcium (8.5–10.5 mg/dL). Normal range for serum intact parathyroid hormone is 10–72 pg/mL. Normal range for serum 1,25-dihydroxyvitamin D is 15–80 pg/mL. Reproduced with permission from Holick MF, copyright 2020.