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. 2020 Jul 16;12(7):2098. doi: 10.3390/nu12072098

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Analysis of Se status from samples of patients suffering from COVID-19 by three complementary serum biomarkers. Serum samples (n = 166) were analyzed from COVID-19 patients (n = 33) by measuring total Se concentration, serum SELENOP level, and activity of secreted GPx3. (A) The Se transporter SELENOP and total Se concentration showed a tight positive linear correlation (r = 0.7896), in agreement with the analysis of (B) GPx3 activity and total Se concentration (r = 0.6239), as well as with (C) GPx3 activity and SELENOP concentration (r = 0.4954). r: Spearman correlation coefficient (2-sided, 2-tailed), **** p < 0.0001.