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Effect of Nem, Cp5 or Cp17 (concentrations used, 12 µM, 25 µg/mL, 13 µg/mL, respectively) on (A,B) migration and (C,D) invasiveness of HT-29 cells in single culture or co-cultured with M2-like macrophages. Data are expressed as mean ± SD of three different experiments. HT-29 cells: **** p < 0.0001 vs. control (single culture); &&&& p < 0.0001 vs. control (co-culture), # p < 0.05, ## p < 0.01, ### p < 0.001, #### p < 0.0001, differences between single and co-culture.
