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. 2020 Jul 5;12(7):1999. doi: 10.3390/nu12071999

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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The impact of synbiotics on (a) the type of stool, (b) the severity of pain, (c) stool pressure, (d) the severity of flatulence, (e) incomplete bowel movements, (f) adverse events assessed by telephone interviewers. All data were collected during telephone interviews. Week 0—screening week before enrollment into the study (baseline). Results are presented as a percentage of patients who reported the severity of symptoms accordingly transformed into new scales described in Table 2. The table (g) presents p-values of a Fisher exact test and Cochran–Mantel–Haenszel test (CHM) and CHM statistic. 0 Synbiotic/0 Placebo—constipation, no or weak pain, flatulence and stool pressure, no feeling of incomplete bowel movements, no adverse events in the synbiotic/placebo group; 1 Synbiotic/1 Placebo—normal stool, intermediate pain, flatulence and stool pressure, presence of a feeling of incomplete bowel movements, presence of adverse events in the synbiotic/placebo group; 2 Synbiotic/2 Placebo—diarrhea, severe pain, flatulence and stool pressure in the synbiotic/placebo group.

The impact of synbiotics on (a) the type of stool, (b) the severity of pain, (c) stool pressure, (d) the severity of flatulence, (e) incomplete bowel movements, (f) adverse events assessed by telephone interviewers. All data were collected during telephone interviews. Week 0—screening week before enrollment into the study (baseline). Results are presented as a percentage of patients who reported the severity of symptoms accordingly transformed into new scales described in Table 2. The table (g) presents p-values of a Fisher exact test and Cochran–Mantel–Haenszel test (CHM) and CHM statistic. 0 Synbiotic/0 Placebo—constipation, no or weak pain, flatulence and stool pressure, no feeling of incomplete bowel movements, no adverse events in the synbiotic/placebo group; 1 Synbiotic/1 Placebo—normal stool, intermediate pain, flatulence and stool pressure, presence of a feeling of incomplete bowel movements, presence of adverse events in the synbiotic/placebo group; 2 Synbiotic/2 Placebo—diarrhea, severe pain, flatulence and stool pressure in the synbiotic/placebo group.