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Percentage of the left ventricle infarcted after 40 minutes of global ischemia and 2 h of reperfusion in Krebs-perfused isolated hearts when exposed to either ischemic preconditioning (IPC) or 1 of 2 doses of ticagrelor. Open symbols represent data from individual hearts, whereas closed symbols represent group averages ± SEM. Only ischemic preconditioning offered any protection against infarction as compared to untreated hearts or those exposed to ticagrelor. *p<0.001 vs other groups
