Figure 5.
miR-21 promotes glioma cell proliferation, migration and invasion. (A and B) The proliferative ability of A172 and AM38 cells transfected with o/e-NC, o/e-NBAT1, miR-21 mimics or co-transfected with o/e-NBAT1 and miR-21 mimics was assessed via the Cell Counting Kit-8 assay. (C and E) The migratory ability of glioma cells transfected with o/e-NC, o/e-NBAT1 or the miR-21 mimics or co-transfected with o/e-NBAT1 and the miR-21 mimics was determined by the Transwell assay. (D and F) The invasive ability of A172 cells increased following transfection with the miR-21 mimics. *P<0.05 vs. o/e-NC; #P<0.05 vs. o/e-NBAT1. miR, microRNA; o/e, overexpression vector; NC, negative control; OD, optical density.