Table 4.
Univariate and multivariate analyses of predictive factors of postoperative complications with CD ≧ IIIa and CR-POPF in the pancreaticoduodenectomy group (N = 68)
| Factor | Postoperative complications with CD ≧ IIIa | CR-POPF | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Univariate | Multivariate | Univariate | Multivariate | |||||||||
| p value | Odds ratio | 95% Cl for Exp (B) | p value | Odds ratio | 95% Cl for Exp (B) | p value | Odds ratio | 95% Cl for Exp (B) | p value | Odds ratio | 95% Cl for Exp (B) | |
| Age (years) | 0.62 | 1.036 | 0.986-1.089 | 0.339 | 1.031 | 0.968-1.099 | ||||||
| Sex (female/male) | 0.669 | 1.240 | 0.463-3.323 | 0.313 | 0.543 | 0.166-1.779 | ||||||
| BMI (kg/m2) | 0.771 | 0.997 | 0.984-1.011 | 0.331 | 1.007 | 0.993-1.022 | ||||||
| Smoking | 0.672 | 1.230 | 0.442-3.210 | 0.818 | 0.871 | 0.266-2.848 | ||||||
| Alcohol | 0.410 | 0.378 | 0.037-3.828 | 0.999 | 0.000 | 0.000 | ||||||
| Disease | 0.811 | 0.964 | 0.715-1.301 | 0.160 | 1.274 | 0.909-1.787 | ||||||
| Diabetes mellitus | 0.209 | 2.114 | 0.657-6.801 | 0.437 | 0.526 | 0.104-2.661 | ||||||
| Antithrombotic drugs | 0.210 | 2.041 | 0.669-6.225 | 0.729 | 1.262 | 0.338-4.707 | ||||||
| Operative time (min) | 0.809 | 0.999 | 0.995-1.004 | 0.095 | 0.995 | 0.998-1.001 | 0.184 | 0.996 | 0.989-1.002 | |||
| Blood loss (g) | 0.980 | 1.000 | 0.999-1.001 | 0.554 | 1.000 | 0.999-1.001 | ||||||
| Intraoperative transfusion | 0.720 | 0.822 | 0.282-2.369 | 0.544 | 0.648 | 0.159-2.637 | ||||||
| Soft pancreas | 0.074 | 2.471 | 0.916-6.666 | 0.065 | 2.656 | 0.941-7.500 | 0.021 | 6.462 | 1.319-31.663 | 0.034 | 5.696 | 1.142-28.149 |
| Albumin (g/l) | 0.287 | 0.603 | 0.237-1.533 | 0.954 | 0.968 | 0.314-2.980 | ||||||
| Lymphocyte (× 103/μl) | 0.321 | 1.000 | 1.000-1.001 | 0.348 | 1.000 | 1.000-1.001 | ||||||
| Total cholesterol (mg/dl) | 0.138 | 0.991 | 0.979-1.003 | 0.148 | 0.988 | 0.972-1.004 | ||||||
| Hemoglobin (g/dl) | 0.533 | 1.046 | 0.907-1.207 | 0.701 | 0.968 | 0.821-1.141 | ||||||
| PNI | 0.836 | 1.006 | 0.951-1.065 | 0.551 | 1.024 | 0.946-1.109 | ||||||
| CONUT score | 0.483 | 0.779 | 0.388-1.565 | 0.162 | 0.504 | 0.193-1.317 | ||||||
| Sarcopenia | 0.642 | 1.255 | 0.482-3.265 | 0.192 | 2.250 | 0.666-7.605 | ||||||
| Frail | 0.054 | 5.104 | 0.975-26.713 | 0.047 | 5.604 | 1.022-30.734 | 0.896 | 1.119 | 0.266-6.092 | |||
Abbreviations: BMI body mass index, CD Clavien-Dindo classification, COUNT controlling nutritional status, CR-POPF clinically relevant postoperative pancreatic fistula, PNI prognostic nutritional index