Table 3.
From pre- to early pregnancy | From early to mid-pregnancy | |||||||
---|---|---|---|---|---|---|---|---|
Quartiles | Crude model | Multivariable modela | Crude model | Multivariable modela | ||||
OR | 95% CI | OR | 95% CI | OR | 95% CI | OR | 95% CI | |
Fruit | ||||||||
First quartile | Reference | Reference | Reference | Reference | ||||
Second quartile | 0.81 | 0.68–0.97 | 0.81 | 0.68–0.98 | 0.88 | 0.73–1.06 | 0.88 | 0.72–1.06 |
Third quartile | 0.75 | 0.62–0.90 | 0.76 | 0.62–0.92 | 1.03 | 0.86–1.23 | 1.01 | 0.84–1.22 |
Fourth quartile | 0.78 | 0.65–0.93 | 0.79 | 0.65–0.95 | 0.84 | 0.69–1.01 | 0.83 | 0.69–1.01 |
P for trend | 0.004 | 0.01 | 0.22 | 0.22 | ||||
Vegetables | ||||||||
First quartile | Reference | Reference | Reference | Reference | ||||
Second quartile | 0.97 | 0.81–1.17 | 1.00 | 0.83–1.22 | 1.08 | 0.90–1.30 | 1.05 | 0.87–1.28 |
Third quartile | 0.94 | 0.78–1.13 | 1.00 | 0.82–1.23 | 0.97 | 0.81–1.17 | 0.95 | 0.78–1.16 |
Fourth quartile | 0.98 | 0.82–1.18 | 1.07 | 0.88–1.32 | 1.03 | 0.86–1.24 | 1.04 | 0.85–1.28 |
P for trend | 0.78 | 0.57 | 0.97 | 0.97 |
aAdjusted for maternal age (continuous variable), pre-pregnancy BMI (< 18.5; 18.5 to 25.0; ≥25.0 kg/m2), parity (never; one or more), educational attainment (high school graduate or less; junior college or vocational college graduate; university graduate or above; others), household income (< 4,000,000; 4,000,000-5,999,999; ≥ 6,000,000 Japanese Yen/year), cigarette smoking (never; stop before pregnancy; stop after pregnancy; current), alcohol drinking (never; former; current), folic acid supplementation during pregnancy (yes vs. no), total fruit, vegetable, meat, fish, grain, potato, bean, and daily product consumption (in quartiles) except for the exposures
All dietary consumption was energy-adjusted using the residual method
P for trends were calculated as trends across categories
BMI Body mass index; LBW Low birth weight; 95% CI 95% confidence interval; OR Odds ratio