Table 1.

Baseline study characteristics

Characteristics	Non-INSTI-based regimens n=15,173	INSTI-based regimens n=5,069	p-value
Age in years (median, IQR)	41 (32, 49)	40 (30, 49)	<0.0001
Males	11,985 (79.0%)	4,050 (79.9%)	0.17
Medicaid insured	2,359 (15.6%)	1,004 (19.8%)	<0.0001
Hypertension	1,677 (11.1%)	691 (13.6%)	<0.0001
Diabetes mellitus	806 (5.3%)	335 (6.6%)	0.0005
Tobacco use	2650 (17.5%)	998 (19.7%)	0.0004
Lipid lowering therapy	2,962 (19.5%)	1,065 (21.0%)	0.022
Drug use	770 (5.1%)	352 (6.9%)	<0.0001
Hepatitis B infection	322 (2.1%)	122 (2.4%)	0.23
Hepatitis C infection	570 (3.8%)	204 (4%)	0.39
Depression	661 (4.4%)	325 (6.4%)	<0.0001

INSTI, integrase strand transfer inhibitor; Unweighted standardized mean differences were <0.1, with the exceptions of tobacco use, Hepatitis C infection, and Medicaid coverage.