Table 1.
Baseline Characteristics
| Parameter | Control (n = 5) | ePAH (n = 4) | PAH (n = 4) | P Value |
|---|---|---|---|---|
| Age, yr | 41.2 (22–60) | 53.5 (44–62) | 47.3 (22–64) | 0.52 |
| Sex, F | 1 | 2 | 3 | 0.31 |
| Race, white | 5 | 3 | 3 | 0.55 |
| Height, cm | 170.9 (160–181.6) | 169.2 (167.6–180.3) | 170.7 (167.6–174) | 0.96 |
| Weight, kg | 86 (72.6–134.6) | 88 (68–107) | 77.3 (56.2–119.7) | 0.85 |
| Years of symptoms | – | 4.2 (1–10) | 8.4 (7–10) | 0.19 |
| FEV1% predicted | 103.7 (90–117) | 87.9 (76–97) | 82.9 (66–95) | 0.12 |
| FVC, % predicted | 105.8 (100–115) | 91.2 (83–118) | 85.6 (64–110) | 0.24 |
| FEV1/FVC | 79 (70–87) | 72 (67–89) | 80 (63–86) | 0.50 |
| mPAP, rest, mm Hg | – | 18 (15–22) | 41.6 (33–63) | 0.01 |
| PVR, rest, dyn · s/cm5 | – | 122.7 (81–143) | 442 (322–548) | 0.001 |
| PCWP, rest, mm Hg | – | 9.3 (7–11) | 10 (7–16) | 0.65 |
| mPAP, exercise, mm Hg | – | 36 (33–38) | – | – |
| PVR, exercise, dyn · s/cm5 | – | 154.6 (136–168) | – | – |
| PCWP, exercise, mm Hg | – | 14.3 (11–18) | – | – |
| 6MWD, m | – | 485.2 (366–595) | 463.2 (382–670) | 0.083 |
Definition of abbreviations: 6MWD = 6-minute-walk distance; ePAH = exercise pulmonary arterial hypertension; mPAP = mean pulmonary arterial pressure; PAH = primary pulmonary arterial hypertension; PCWP = pulmonary capillary wedge pressure; PVR = pulmonary vascular resistance.
Continuous variables are represented as mean (minimum–maximum). Categorical variables are represented as counts.