Table 1.
Demographic Features and Structural Data (Mean ± SD) in 4 Subject Groups
| Affected AION | Fellow AION | Glaucoma | Normal | AF | AN | GN | AG | |
|---|---|---|---|---|---|---|---|---|
| Visual acuity (logMAR) | 0.98 ± 1.01 | 0.19 ± 0.46 | 0.28 ± 0.37 | 0.03 ± 0.09 | <0.001 | <0.001 | 0.22 | <0.001 |
| Age (y) | 55.46 ± 11.38 | 54.68 ± 11.29 | 60.38 ± 12.27 | 55.26 ± 15.69 | 0.78 | >0.99 | >0.99 | 0.95 |
| Gender (male:female) | 21:16 | 17:17 | 27:20 | 22:32 | 0.31 | |||
| Axial length (mm) | 22.7 ± 0.88 | 22.96 ± 0.91 | 23.16 ± 0.89 | 22.8 ± 1.0 | >0.99 | >0.99 | 0.27 | 0.29 |
| Total GCC (µm) | 75.04 ± 15.0 | 94.98 ± 8.4 | 75.54 ± 21.2 | 99.09 ± 5.7 | <0.001 | <0.001 | <0.001 | >0.99 |
| Superior GCC (µm) | 74.18 ± 16.5 | 93.83 ± 9.0 | 77.70 ± 22.3 | 98.83 ± 6.1 | 0.001 | <0.001 | 0.001 | >0.99 |
| Inferior GCC (µm) | 75.94 ± 14.2 | 96.13 ± 8.2 | 72.01 ± 21.02 | 99.21 ± 5.7 | <0.001 | <0.001 | <0.001 | >0.99 |
| Average RNFL (µm) | 77.03 ± 23.4 | 108.85 ± 22.0 | 76.07 ± 15.4 | 109.19 ± 12.3 | <0.001 | <0.001 | <0.001 | >0.99 |
| Superior RNFL (µm) | 74.89 ± 23.5 | 108.21 ± 25.6 | 79.43 ± 18.1 | 110.89 ± 13.8 | <0.001 | <0.001 | <0.001 | >0.99 |
| Inferior RNFL (µm) | 79.94 ± 27.9 | 109.53 ± 21.3 | 74.04 ± 15.3 | 103.74 ± 21.4 | <0.001 | <0.001 | <0.001 | >0.99 |
Comparisons are based on linear mixed model analysis.
AF, Comparison between AION (anterior ischemic optic neuropathy) and fellow eye; AG, comparison between AION and glaucoma; AN, comparison between AION and normal subjects; FN, comparison between fellow eye and normal subjects; GCC, ganglion cell complex; GN, comparison between glaucoma and normal subjects; RNFL, retinal nerve fiber layer.