Table 1.
Study Parameters (Independent Variables), Normal Distribution, and Range of Values
| Type | Parameters | Normal Distribution Mean ± SD | Value Range‡ (min, max) | Ref. |
|---|---|---|---|---|
| Morphometric | LC radius (mm) | 1.2 ± 0.12 | (0.83, 1.6) | Rosenberg et al.68 |
| Pore size (µm2) | 5400 ± 2400 | (1200, 10,500) | Brown et al.69 | |
| Anisotropy* | 0.0037 ± 0.55 | (–1.8, 2) | Roberts et al.70 | |
| Cup depth† (mm) | 0.2 ± 0.1 | (0, 0.5) | Jonas and Budde71 | |
| Hemodynamics | Perfusion pressure (mm Hg) | 50 ± 9 | (23, 75) | Mozaffarieh et al.72 |
| Biomechanics | IOP (mm Hg) | Stepwise in increments of 5 mm Hg | (10, 55) | — |
| CSFP (mm Hg) | 13.0 ± 2 | (7, 19) | Feola et al.3 | |
| LC stiffness (MPa) | 0.41 ± 0.2 | (0.08, 1.00) | Zhang et al.29 | |
| Scleral stiffness (ratio)§ | 1 ± 0.2 | (0.22, 1.53) | Girard et al.50 |
*
Positive values indicate a radial arrangement of the microcapillaries; negative values, a tangential arrangement; and 0, an isotropic arrangement.
†
Positive values denote posterior cupping (downward).
‡
Minimum values of LC radius, pore size, cup depth, perfusion pressure, IOP, CSFP, LC, and scleral stiffness are bounded at 0.
§
This ratio is a multiplier of normal stiffness values (C1 = 0.802, C2 = 0, C3 = 0.0127, C4 = 1098) for Mooney–Rivlin Von Mises distributed fibers.