Table 3.
Multivariable Regression Results
| Ranking of the Influence of Input Parameters with Respect to | Rank | Parameter | Beta Coefficients |
|---|---|---|---|
| Average oxygen concentration | 1 | Prefusion pressure | +4.79 |
| 2 | LC radius | –3.42 | |
| 3 | Pore size | –1.65 | |
| 4 | Anisotropy | +0.68 | |
| 5 | IOP | –0.49 | |
| 6 | LC stiffness | +0.30 | |
| 7 | Scleral stiffness | +0.21 | |
| 8 | Cup depth | –0.11 | |
| 9 | CSFP | –0.05 | |
| Compressive strain* | 1 | IOP | +0.46 |
| 2 | LC stiffness | –0.32 | |
| 3 | LC radius | +0.27 | |
| 4 | CSFP | +0.22 | |
| 5 | Scleral stiffness | –0.24 | |
| 6 | Cup depth | +0.21 | |
| LC posterior displacement* | 1 | IOP | +0.70 |
| 2 | LC stiffness | –0.43 | |
| 3 | LC radius | +0.41 | |
| 4 | Cup depth | –0.14 | |
| 5 | Scleral stiffness | –0.08 | |
| 6 | CSFP | –0.05 | |
| Changes in average oxygen concentration under elevated IOP† | 1 | Cup depth | +1.28 |
| 2 | LC stiffness | –1.05 | |
| 3 | Radius | +0.45 | |
| 4 | Perfusion pressure | –0.25 | |
| 5 | Anisotropy | –0.038 | |
| 6 | Scleral stiffness | –0.033 | |
| 7 | Pore Size | –0.008 |
*
Only six biomechanically relevant parameters were included in the rankings.
†
Because IOP and CSFP were fixed, they were excluded from this ranking.