Figure 5.

Inhibition of JAK/STAT or overexpression of miR-19b decreased the expression of DC maturation and of the Th2 inflammatory response genes induced by AC. The mRNA expression levels of IL-1, IL-5, IL-6, IL-8, IL-13, IL-33, ST2, TSLP, STAT3, OX40, OX40L, and CD11c respectively in (A) conjunctiva, (B) cornea, and (C) cervical lymph nodes from mice of the PBS, AC, AC + CYT387, AC + miR-19b, and AC + control miR groups were determined by RT-qPCR. All data were representative of at least 3 independent experiments.