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. 2020 Jun 25;219(8):e202003038. doi: 10.1083/jcb.202003038

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© 2020 Chastney et al.

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms/). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license, as described at https://creativecommons.org/licenses/by-nc-sa/4.0/).

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Figure 2. — Hierarchical clustering of BioID data. Hierarchical clustering was performed on the 147 proteins identified in the proximity-dependent adhesome and the results are displayed as a heatmap. BioID baits were clustered using the Jaccard distance of the presence (BFDR ≤ 0.05) or absence (BFDR > 0.05) of prey. Prey proteins were clustered using the Euclidean distance of log₂ fold-change enrichment over BirA* control. Log₂ fold-changes of prey proteins are displayed as a heatmap. Dendrograms were split to identify clusters of baits (B1–B5, color coded) and prey (P1–P16). N.D., not detected.