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. Author manuscript; available in PMC: 2020 Aug 4.
Published in final edited form as: Ann Diagn Pathol. 2020 Feb 15;45:151481. doi: 10.1016/j.anndiagpath.2020.151481

Fig. 6.

Fig. 6.

Examples of aberrant E-cadherin expression in lobular carcinoma in situ. A. Most often, aberrant E-cadherin expression is characterized by weak, partial, fragmented, or beaded membrane staining. B. In some cases there is more extensive membranous staining as well as diffuse cytoplasmic staining. C. An example of aberrant E-cadherin expression in which some cells show a perinuclear, dot-like pattern of staining (note normal membranous expression of E-cadherin in the duct on the right side of the image).