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. 2020 Jul 28;14:212. doi: 10.3389/fncel.2020.00212

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Copyright © 2020 Kitase, Sato, Arai, Onoda, Ueda, Go, Mimatsu, Jabary, Suzuki, Ito, Saito, Hirakawa, Mukai, Nagamura-Inoue, Takahashi, Tsuji and Hayakawa.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Characters of the Ameroid constrictor. (A) Ameroid constrictor. An ameroid constrictor (AC) contains casein inside, has a notch and a hole in the center and is covered with a wide titanium ring. Its size is approximately 3.0 mm in diameter (a); the tool has a center hole of 0.4 mm (b) and a width of about 1.3 mm (c). This casein protein swells slowly when it absorbs water. (B) Installation of AC. The figure shows that the left and right ovarian/uterine arteries were sequentially detached from the vein, and an AC was placed in each of the four locations of the artery. (C) The change of diameter in AC. The graph shows the diameter of the center hole in an AC in a physiological saline environment of 37°C in vitro. The hole shrank to approximately 1/5 its original size in 1 day and to about 1/10 in 3 days. The photograph below shows the change of its shape over time in saline at 37°C.