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. 2020 Apr 25;61(4):35. doi: 10.1167/iovs.61.4.35

Table 3.

Absolute Risk of Metastatic Death

Absolute Risk (95% CI)
Age <81 yr at Treatment Age >80 yr at Treatment
Years After Treatment Years After Treatment
LBTD, mm 2 5 10 2 5 10
Disomy-3 Melanoma
<10.1 0.1 (0, 0.5) 0.7 (0, 1.6) 2.1 (0.7, 4) 0.1 (0, 0.5) 0.6 (0, 1.4) 1.4 (0.4, 2.6)
10.1–12.0 0.8 (0.2, 1.7) 1.7 (0.5, 3.4) 3.7 (1.5, 6.7) 0.7 (0.1, 1.6) 1.5 (0.5, 3) 2.7 (1.1, 4.8)
12.1–14.0 1.1 (0, 2.5) 3.3 (1, 6) 6.5 (2.7, 11) 1 (0, 2.4) 2.9 (0.9, 5.3) 4.9 (2, 8.3)
14.1–16.0 1.5 (0, 4) 5.3 (1.8, 9.6) 11 (4.9, 18) 1.5 (0, 3.8) 4.6 (1.6, 8.4) 8 (3.7, 13)
16.1–18.0 3.1 (0, 8.7) 12 (5.1, 21) 17 (8, 28) 2.9 (0, 8.3) 11 (4.5, 19) 14 (6.5, 22)
18.1–28.0 6 (0, 14) 12 (2.4, 25) 18 (6.2, 32) 5.7 (0, 14) 11 (2.3, 22) 15 (4.6, 26)
Monosomy-3 Melanoma
<10.1 2.5 (0.6, 5.2) 13 (6.4, 21) 26 (13, 41) 2.4 (0.5, 5) 11 (5.5, 18) 19 (9.6, 30)
10.1–12.0 5 (2.2, 8.4) 20 (12, 28) 37 (22, 51) 4.8 (2.1, 8.1) 18 (11, 25) 28 (17, 38)
12.1–14.0 8 (4.9, 12) 33 (24, 42) 53 (38, 65) 7.9 (4.7, 12) 29 (21, 37) 42 (30, 51)
14.1–16.0 13 (9.2, 18) 42 (35, 50) 66 (55, 75) 13 (8.8, 17) 37 (30, 44) 52 (43, 60)
16.1–18.0 21 (16, 27) 59 (51, 67) 77 (67, 85) 20 (15, 26) 53 (46, 61) 64 (56, 71)
18.1–28.0 32 (26, 38) 70 (63, 78) 80 (73, 87) 31 (25, 37) 64 (57, 71) 71 (64, 77)
Unknown Chromosome 3 Status
<10.1 0.6 (0.2, 1.1) 3.1 (2.1, 4.2) 6.6 (5, 8.3) 0.6 (0.2, 1) 2.7 (1.8, 3.6) 4.7 (3.6, 6)
10.1–12.0 2 (1.2, 3) 7 (5.3, 8.9) 13 (10, 15) 1.9 (1.1, 2.9) 6.1 (4.6, 7.8) 9.7 (7.8, 12)
12.1–14.0 4 (2.6, 5.4) 15 (13, 18) 25 (21, 28) 3.8 (2.5, 5.1) 14 (11, 16) 19 (17, 22)
14.1–16.0 7.9 (5.7, 10) 25 (22, 30) 41 (36, 45) 7.6 (5.5, 9.8) 22 (19, 26) 32 (28, 36)
16.1–18.0 15 (11, 19) 43 (37, 48) 55 (50, 61) 14 (11, 18) 38 (33, 43) 46 (41, 51)
18.1–28.0 25 (21, 30) 56 (50, 62) 65 (59, 70) 24 (20, 29) 51 (45, 56) 56 (51, 62)