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. 2020 Jul 28;7:426. doi: 10.3389/fvets.2020.00426

Table 4.

Summary comparing the results among BTY, ZZ-R 127, LFBK-αVβ6, and IB-RS-2.

Cell type
BTY ZZ-R 127 LFBK-αVβ6 IB-RS-2
Duration of FMDV sensitivity 3–4 weeks per batch >100 passages >100 passages >100 passages
Duration of SVDV sensitivity ND ND >100 passages >100 passages
Sensitivity of cell lines FMD/A/IRN/24/2012 5.8 5.7 5.8 4.3
FMD/O/KUW/4/2016 7.9 7.7 7.7 6.4
(Avg. Log10 TCID50/mL) SVD/UKG/77/80 ND ND 5.2 4.5
Detected FMDV epithelium suspensions 31/32 30/32 32/32 ND
Detected O/CATHAY epithelium suspensions ND 2/8 8/8 1/8
Detected O/CATHAY diagnostic submissions 0/26 ND 19/26 5/26
Susceptibility to other vesicular viruses None VESV, VSV VESV, VSV, SVV VESV, VSV, SVV
Matrices causing cytotoxicity None Whole blood Whole blood Whole blood

ND, not done.