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. 2020 Jul 13;20(3):2774–2782. doi: 10.3892/etm.2020.9000

Figure 4.

Figure 4

KDM6A overexpression suppresses hepatocellular carcinoma cell tumorigenesis in vivo. (A) Representative images of the tumors generated by empty vector- and KDM6A overexpression vector-transfected Huh7 cells. Tumor (B) volume and (C) weight. (D) The effect of KDM6A overexpression on the protein expression levels of TGF-β, p-smad2, Ki67 and PCNA in tumor samples. *P<0.05, **P<0.01 and ***P<0.001 vs. vector. KDM6A, lysine demethylase 6A; TGF-β, transforming growth factor-β; p, phosphorylated; PCNA, proliferating cell nuclear antigen; ns, not significant.